BChE-IN-10

Names

[ CAS No. ]:
2185837-61-8

[ Name ]:
BChE-IN-10

Biological Activity

[Description]:

BChE-IN-10 (compound 6) is a potent butyrylcholinesterase (BChE) mixed-type inhibitor with an IC50 value of 6.4 μM. BChE-IN-10 can be isolated from Bletilla striata. BChE-IN-10 can be used for the research of Alzheimer's disease (AD)[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

BChE:6.4 μM (IC50)


[References]

[1]. Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H20O5

[ Molecular Weight ]:
376.40

Related Compounds