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horminone

Names

[ CAS No. ]:
21887-01-4

[ Name ]:
horminone

[Synonym ]:
1,4-Phenanthrenedione, 4b,5,6,7,8,8a,9,10-octahydro-3,10-dihydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aS,10R)-
7ALPHA,12-DIHYDROXY-8,12-ABIETADIENE-11,14-DIONE
Hormine
(7α)-7,12-Dihydroxyabieta-8,12-diene-11,14-dione
HORMINON
horminone
Hydroxyroyleanon

Biological Activity

[Description]:

Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Inés Nicolás, et al. Theoretical study of the structure and antimicrobial activity of horminone. Theoretical Biochemistry and Biophysics. 2003.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
469.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H28O4

[ Molecular Weight ]:
332.434

[ Flash Point ]:
251.7±25.2 °C

[ Exact Mass ]:
332.198761

[ PSA ]:
74.60000

[ LogP ]:
5.04

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.565

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds