Z-Val-Asp-Val-Ala-Asp-AFC

Names

[ CAS No. ]:
219138-08-6

[ Name ]:
Z-Val-Asp-Val-Ala-Asp-AFC

[Synonym ]:
Z-Val-Asp-Ala-Asp-AFC
PASE-2 SUBSTRATE I,FLUOROGENIC
Z-VAL-ASP-VAL-ALA-ASP-AFC

Biological Activity

[Description]:

Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₉H₄₅F₃N₆O₁₃

[ Molecular Weight ]:
862.80

[ Exact Mass ]:
862.30000

[ PSA ]:
288.64000

[ LogP ]:
4.29330

[ Storage condition ]:
-15°C

Z-Val-Asp-Val-Ala-Asp-AFC

Names

Biological Activity

Chemical & Physical Properties

Related Compounds