Boc-Cys(Trt)-OH

Names

[ CAS No. ]:
21947-98-8

[ Name ]:
Boc-Cys(Trt)-OH

[Synonym ]:
L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)-
MFCD00038251
(R)-2-(tert-Butoxycarbonylamino)-3-(tritylthio)propanoic acid
N-[(1,1-dimethylethoxy)carbonyl]-S-trityl-L-cysteine
n-(tert-butoxycarbonyl)-s-trityl-l-cysteine
S-trityl-N-Boc-(R)-cysteine
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-S-trityl-L-cysteine
N-t-butyloxycarbonyl-S-trityl-L-cysteine
S-trityl-N-Boc-cysteine
N-t-butoxycarbonyl-S-trityl-L-Cysteine
Boc-S-trityl-L-cysteine
Boc-Cys(Trt)-OH
EINECS 244-674-6
N-Boc-S-trityl-L-cysteine

Biological Activity

[Description]:

(R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid is a cysteine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
610.9±55.0 °C at 760 mmHg

[ Melting Point ]:
143-146 °C(lit.)

[ Molecular Formula ]:
C₂₇H₂₉NO₄S

[ Molecular Weight ]:
463.589

[ Flash Point ]:
323.3±31.5 °C

[ Exact Mass ]:
463.181732

[ PSA ]:
100.93000

[ LogP ]:
7.52

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.596

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Preparation

Articles

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Bioorg. Med. Chem. Lett. 17 , 3921-4, (2007)

Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors...