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Thalidomide-Piperazine 5-fluoride

Names

[ CAS No. ]:
2222114-22-7

[ Name ]:
Thalidomide-Piperazine 5-fluoride

Biological Activity

[Description]:

Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Hexiang Wang, et al. Degradation of androgen receptor (ar) by conjugation of ar antagonists with e3 ligase ligand and methods of use. WO2021058017A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H17FN4O4

[ Molecular Weight ]:
360.34

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds