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Hsp90-Cdc37-IN-1

Names

[ CAS No. ]:
2227303-22-0

[ Name ]:
Hsp90-Cdc37-IN-1

Biological Activity

[Description]:

Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance, with an IC50 of 140 nM.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 140 nM (Hsp90-Cdc37)[1]

[References]

[1]. Jin L, et al. Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₃H₅₇FN₂O₆S

[ Molecular Weight ]:
748.99

Related Compounds