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Deltasonamide 2 (TFA)

Names

[ CAS No. ]:
2235358-74-2

[ Name ]:
Deltasonamide 2 (TFA)

Biological Activity

[Description]:

Deltasonamide 2 TFA is a PDEδ inhibitor with a Kd of ~385 pM and an EC50 of 1.24 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

Kd: ~385 pM (PDEδ)[1] EC50: 1.24 ± 0.06 μM (PDEδ)[1]

[References]

[1]. Klein CH, et al. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell linesharboring oncogenic KRas. Int J Cancer. 2019 Feb 15;144(4):767-776.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₀ClF₃N₆O₆S₂

[ Molecular Weight ]:
761.27

[ Storage condition ]:
2-8℃

Related Compounds