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isotianil

Names

[ CAS No. ]:
224049-04-1

[ Name ]:
isotianil

[Synonym ]:
3,4-Dichloro-2 inverted exclamation marka-cyano-1,2-thiazole-5-carboxanilide
5-Isothiazolecarboxamide,3,4-dichloro-N-(2-cyanophenyl)
3,4-dichloro-N-(2-cyanophenyl)isothiazole-5-carboxamide
T5NSJ CVMR BCN& DG EG
3,4-Dichloro-N-(2-cyanophenyl)-5-Isothiazolecarboxamide
3,4-dichloro-2-cyano-1,2-thiazole-5-carboxanilide
3,4-dichloro-isothiazol-5-carboxylic acid-(2-cyano-phenyl)-amide
3,4-dichloro-N-(2-cyano-phenyl)-isothiazol-5-carboxamide
3,4-Dichloro-N-(2-cyanophenyl)-1,2-thiazole-5-carboxamide
3,4-dichloro-2’-cyano-1,2-thiazole-5-carboxanilide
5-Isothiazolecarboxamide, 3,4-dichloro-N-(2-cyanophenyl)-
3,4-dichloro-isothiazole-5-cyanoanilide
UNII-482Y0NQC01
isotianil
Isotianil [ISO]
3,4-Dichloro-2'-cyano-1,2-thiazole-5-carboxanilide

Biological Activity

[Description]:

Isotianil is a plant defense inducer that has no direct antimicrobial effect but instead activates typical plant defense responses. Isotianil can be used as a plant protection agent for controlling rice blast[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Isotianil (0.1-100 ppm, 2 days)可以诱导水稻组织中内源性的脂氧合酶、苯丙氨酸解氨酶和几丁质酶等植物抗病相关酶的积累。诱导抗病性相关基因，包括 WRKY45[1]。 Isotianil 在较低剂量下对叶瘟病具有良好的预防效果，显示出对多种细菌性疾病的植物抗性诱导作用，包括由伯克霍尔德菌引起的细菌性幼苗腐烂等[1]。 Isotianil 有效保护苗期小麦植株免受有毒的 MoT分离株 BR32 的侵害，可防止 MoT的侵入性生长，使其无法从最初受到攻击的表皮细胞进展到叶肉[2].

[References]

[1]. Ogawa M, Kadowaki A, Yamada T, et al. Applied development of a novel fungicide isotianil (STOUT)[J]. Sumitomo Kagaku, 2011, 1: 1-15.

[2]. Katharina Portz, et al. Wheat blast caused by Magnaporthe oryzae pathovar Triticum is efficiently controlled by the plant defence inducer isotianil. Journal of Plant Diseases and Protection volume 128, pages249-259 (2021).

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
322.8±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H5Cl2N3OS

[ Molecular Weight ]:
298.148

[ Flash Point ]:
149.0±27.9 °C

[ Exact Mass ]:
296.953033

[ PSA ]:
97.51000

[ LogP ]:
2.13

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.675

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H319-H334

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36-43

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds