MALT1-IN-8

Names

[ CAS No. ]:
2244109-29-1

[ Name ]:
MALT1-IN-8

Biological Activity

[Description]:

MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> NF-κB >> MALT1

[Target]

IC50: 2 nM (MALT1 protease)[1]


[References]

[1]. Nathanael S. Gray, et al. Inhibitors of malt1 and uses thereof. WO2018165385A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H15Cl2N7O

[ Molecular Weight ]:
440.29

Related Compounds