DKFZ-633

Names

[ Name ]:
DKFZ-633

Biological Activity

[Description]:

DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs; DKFZ-633 is a useful chemical probe to pull down active endogenous KLK6.

[References]

References 1. De Vita E, et al. J Med Chem. 2018 Sep 28. doi: 10.1021/acs.jmedchem.8b01106. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₄N₄O₃

[ Molecular Weight ]:
440.503

Related Compounds

DKFZ-251
DKFZ-748
EML-633
KRN-633
1,5-Naphthalenedisulfonic acid, 2-[2-[8-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-1-hydroxy-3,6-disulfo-2-naphthalenyl]diazenyl]-, sodium salt (1:), reaction products with sodium 2,4-diamino-5-[2-[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]benzenesulfonate (1:)
albumin blue 633
4-(2-thienyl)dihydro-2H-pyran-2,6(3H)-dione
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
4-Nitrobenzeneacetic acid 2-[6-[[2-(methoxycarbonyl)phenyl]amino]-5-nitro-4-pyrimidinyl]hydrazide
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine