β-Glucuronide-dPBD-PEG5-NH2 TFA
Names
[ CAS No. ]:
2246364-63-4
[ Name ]:
β-Glucuronide-dPBD-PEG5-NH2 TFA
Biological Activity
[Description]:
β-Glucuronide-dPBD-PEG5-NH2 TFA is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2 TFA, as a prodrug of cIRCR201-dPBD, reduces side effects[1].
[Related Catalog]:
[Target]
Drug-linker conjugates for ADC, Apoptosis[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C80H102F3N7O37
[ Molecular Weight ]:
1810.69