JWD-065
Names
[ CAS No. ]:
2250287-34-2
[ Name ]:
JWD-065
Biological Activity
[Description]:
JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.
[References]
1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55. 2. Miduturu CV et al. Chem Biol. 2011;18:868–879.
Chemical & Physical Properties
[ Molecular Formula ]:
C24H26N6O2S
[ Molecular Weight ]:
462.572