3-(Trifluoromethyl)benzoyl chloride

Names

[ Name ]:
3-(Trifluoromethyl)benzoyl chloride

[Synonym ]:
m-Toluoyl chloride, α,α,α-trifluoro-
m-Trifluiromethylbenzoyl chloride
α,α,α-Trifluoro-m-tolyl Chloride
3-(Chlorocarbonyl)benzotrifluoride
Benzoyl chloride, 3-(trifluoromethyl)-
trifluoromethylbenzoyl chloride
GVR CXFFF
m-(Trifluoromethyl)benzoyl chloride
3-(trifluoromethyl)-benzoyl chloride
3-(trifluoromethyl)-benzoylchlorid
metha-trifluoromethylbenzoyl chloride
3-CF3PhCOCl
MTF-BOC
3-trifluoromethylbenzoic acid chloride
EINECS 218-844-5
α,α,α-Trifluoro-m-toluoyl chloride
MFCD00000680
3-(Trifluoromethyl)benzoyl chloride
m-trifluoromethyl-benzoyl chloride

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
185.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₄ClF₃O

[ Molecular Weight ]:
208.565

[ Flash Point ]:
75.5±27.3 °C

[ Exact Mass ]:
207.990280

[ PSA ]:
17.07000

[ LogP ]:
3.27

[ Vapour Pressure ]:
0.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.467

[ Water Solubility ]:
decomposes

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R29;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S8

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors

Bioorg. Med. Chem. Lett. 19(23) , 6519-23, (2009)

Optimization of initial lead compound 1 provided a series of pyrazolo[1,5- a]pyrimidines 2 as potent B-Raf kinase inhibitors.