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Cathepsin Inhibitor 1

Names

[ CAS No. ]:
225120-65-0

[ Name ]:
Cathepsin Inhibitor 1

[Synonym ]:
Cathepsin Inhibitor 1

Biological Activity

[Description]:

Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[References]

[1]. Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3.

Chemical & Physical Properties

[ Density]:
1.23±0.1 g/cm3 (20 ºC 760 Torr)

[ Molecular Formula ]:
C20H24ClN5O2

[ Molecular Weight ]:
401.89000

[ Exact Mass ]:
401.16200

[ PSA ]:
106.79000

[ LogP ]:
3.76698

[ Storage condition ]:
-20℃

Safety Information

[ HS Code ]:
29242990


Related Compounds