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DMNPE-4 AM-caged-calcium

Names

[ CAS No. ]:
2253744-58-8

[ Name ]:
DMNPE-4 AM-caged-calcium

Biological Activity

[Description]:

DMNPE-4 AM-caged-calcium, photolabile analogues of EGTA, is an extremely effective Ca2+ selective cage, with a Kd for Ca2+ of 48 nM and 19 nM at pH 7.2 and pH 7.4, respectively. DMNPE-4 AM-caged-calcium has a lower affinity for Ca2+ (Kd=~2 nM) after photolysis[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Ellis-Davies GCR, et, al. Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium. 2006 Jan;39(1):75-83.

[2]. DelPrincipe F, et, al. Two-photon and UV-laser flash photolysis of the Ca2+ cage, dimethoxynitrophenyl-EGTA-4. Cell Calcium. 1999 Jan;25(1):85-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H47N3O22

[ Molecular Weight ]:
849.74

Related Compounds