Antiparasitic agent-4

Names

[ CAS No. ]:
2253996-66-4

[ Name ]:
Antiparasitic agent-4

Biological Activity

[Description]:

Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 8.51 μM (L. infantum), 2.20 μM (T. cruzi)[1]


[References]

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H13N3O2

[ Molecular Weight ]:
279.29

Related Compounds