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RORγ agonist 1

Names

[ CAS No. ]:
2260631-91-0

[ Name ]:
RORγ agonist 1

Biological Activity

[Description]:

RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR

Research Areas >> Cancer

[References]

[1]. Lu B, et al. Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity. J Med Chem. 2021 Oct 28;64(20):14983-14996.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₇ClF₄N₂O₄S

[ Molecular Weight ]:
611.05

Related Compounds