Pomalidomide 4'-PEG3-azide
Names
[ CAS No. ]:
2271036-46-3
[ Name ]:
Pomalidomide 4'-PEG3-azide
Biological Activity
[Description]:
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach[1].
[Related Catalog]:
[Target]
Cereblon
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H26N6O7
[ Molecular Weight ]:
474.47
[ Storage condition ]:
2-8°C