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Diflumidone

Names

[ CAS No. ]:
22736-85-2

[ Name ]:
Diflumidone

[Synonym ]:
Methanesulfonanilide,3'-benzoyl-1,1-difluoro
Diflumidonum [INN-Latin]
Diflumidone
R 807 (Pharmaceutical)
3'-Benzoyl-1,1-difluoromethansulfonanilid
Diflumidone [INN:BAN]
R 807
N-(3-Benzoylphenyl)-1,1-difluormethansulfonamid
3-Benzoyl-difluormethansulfonanilid
Diflumidona [INN-Spanish]
3'-Benzoyl-1,1-difluoro-methanesulfonanilide
Diflumidone Sodium

Biological Activity

[Description]:

Diflumidone is a non-steroidal antiinflammatory drug.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Gomez EC, et al. Effect of topical diflumidone on ultraviolet-light-induced erythema. Dermatologica. 1981;162(3):175-82.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.419g/cm3

[ Boiling Point ]:
438.8ºC at 760mmHg

[ Molecular Formula ]:
C14H11F2NO3S

[ Molecular Weight ]:
311.30400

[ Flash Point ]:
219.2ºC

[ Exact Mass ]:
311.04300

[ PSA ]:
71.62000

[ LogP ]:
4.03570

[ Vapour Pressure ]:
6.7E-08mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PB0507500
CHEMICAL NAME :
Methanesulfonanilide, 3'-benzoyl-1,1-difluoro-
CAS REGISTRY NUMBER :
22736-85-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H11-F2-N-O3-S
MOLECULAR WEIGHT :
311.32
WISWESSER LINE NOTATION :
FYFSWMR CVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,132,1976

Safety Information

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%