Vobasan-17-oic acid,19,20-dihydro-3-oxo-, methyl ester, (20a)-
Names
[ CAS No. ]:
2299-26-5
[ Name ]:
Vobasan-17-oic acid,19,20-dihydro-3-oxo-, methyl ester, (20a)-
[Synonym ]:
3-oxo-19,20-dihydro-vobasan-17-oic acid methyl ester
tabernaemontanine
Chemical & Physical Properties
[ Density]:
1.176g/cm3
[ Boiling Point ]:
515.9ºC at 760mmHg
[ Molecular Formula ]:
C21H26N2O3
[ Molecular Weight ]:
354.44300
[ Flash Point ]:
265.8ºC
[ Exact Mass ]:
354.19400
[ PSA ]:
62.40000
[ LogP ]:
2.98030
[ Vapour Pressure ]:
9.47E-11mmHg at 25°C
[ Index of Refraction ]:
1.581
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZB1635000
- CHEMICAL NAME :
- Vobasan-17-oic acid, 19,20-dihydro-3-oxo-, methyl ester, (20-alpha)-
- CAS REGISTRY NUMBER :
- 2299-26-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H26-N2-O3
- MOLECULAR WEIGHT :
- 354.49
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 28,697,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 28,697,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 24 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 28,697,1970