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(S,R,S)-AHPC-C6-PEG3-butyl-N3

Names

[ CAS No. ]:
2300155-90-0

[ Name ]:
(S,R,S)-AHPC-C6-PEG3-butyl-N3

[Synonym ]:
L-Prolinamide, N-[6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-1-oxohexyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
N-[6-(2-{2-[(6-Azidohexyl)oxy]ethoxy}ethoxy)hexanoyl]-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide

Biological Activity

[Description]:

(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

Chemical & Physical Properties

[ Molecular Formula ]:
C38H59N7O7S

[ Molecular Weight ]:
757.983

[ Exact Mass ]:
757.419678

[ LogP ]:
2.45

Related Compounds