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PSMA-ALB-56

Names

[ CAS No. ]:
2306049-48-7

[ Name ]:
PSMA-ALB-56

Biological Activity

[Description]:

PSMA-ALB-56 is a PSMA-targeting radioligand designed by combining the glutamate-urea PSMA-binding entity and an albumin binder[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Traditional Cytotoxic Agents


[In Vivo]

PSMA-ALB-56 accumulates much faster in tumor tissues and is more efficiently cleared from the blood and background tissues, which results in excellent tumor-to-background contrast already 4 hours after injection. PSMA-ALB-56 increases median survival in mice[1].

[References]

[1]. Umbricht CA, et al. Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy. Mol Pharm. 2018;15(6):2297-2306.

Chemical & Physical Properties

[ Molecular Formula ]:
C66H95N11O18

[ Molecular Weight ]:
1330.52


Related Compounds