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(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2)

Names

[ CAS No. ]:
2341796-74-3

[ Name ]:
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2)

Biological Activity

[Description]:

E3 ligase Ligand-Linker Conjugates 21 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 21 can be used to design PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

VHL


[References]

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H51N5O4S

[ Molecular Weight ]:
613.85

[ Storage condition ]:
2-8°C

Related Compounds