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SPL-410

Names

[ CAS No. ]:
2351886-00-3

[ Name ]:
SPL-410

Biological Activity

[Description]:

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

IC50: 9 nM (SPPL2a)[1].


[References]

[1]. Velcicky J, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. ACS Med Chem Lett. 2019 May 23;10(6):887-892.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H31F3N2O4S

[ Molecular Weight ]:
500.57

Related Compounds