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Fmoc-Gly-Gly-Phe-OtBu

Names

[ CAS No. ]:
236426-37-2

[ Name ]:
Fmoc-Gly-Gly-Phe-OtBu

Biological Activity

[Description]:

Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[References]

[1]. Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H35N3O6

[ Molecular Weight ]:
557.64

Related Compounds