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SMARCA-BD ligand 1 for Protac dihydrochloride

Names

[ CAS No. ]:
2369053-68-7

[ Name ]:
SMARCA-BD ligand 1 for Protac dihydrochloride

Biological Activity

[Description]:

SMARCA-BD ligand 1 for Protac dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

SMARCA2[1]


[References]

[1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H19Cl2N5O

[ Molecular Weight ]:
344.24

[ Storage condition ]:
2-8°C

Related Compounds