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KB02-COOH

Names

[ CAS No. ]:
2375196-30-6

[ Name ]:
KB02-COOH

Biological Activity

[Description]:

KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 (HY-129917) and KB02-SLF (HY-129610)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H14ClNO4

[ Molecular Weight ]:
283.71

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds