Pomalidomide-C6-O-C5-O-C4-COOH

Names

[ CAS No. ]:
2375774-54-0

[ Name ]:
Pomalidomide-C6-O-C5-O-C4-COOH

Biological Activity

[Description]:

Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and linker. Pomalidomide-C6-O-C5-O-C4-COOH can be used for the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Steinebach C , et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824.  

Chemical & Physical Properties

[ Molecular Formula ]:
C29H41N3O8

[ Molecular Weight ]:
559.65

Related Compounds