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CD73-IN-3

Names

[ CAS No. ]:
2375815-63-5

[ Name ]:
CD73-IN-3

Biological Activity

[Description]:

CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

CD73-IN-3 inhibits CD73 activity in human serum with an EC50 of 0.213 μM. CD73-IN-3 inhibits CD73 activity in human serum by 56.8%, 71.7% and 76.9% at 0.52 μM, 1.56 μM, 4.68 μM,respectively[1]. In Calu6 human cell assay against CD73, the IC50 for CD73-IN-3 against CD73 is 0.0073 uM[1].

[References]

[1]. Robert Dean Dally, et al. Cd73 inhibitors. Patent WO2019168744 A1.

Chemical & Physical Properties

No Any Chemical & Physical Properties


Related Compounds