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TRPA1-IN-1

Names

[ CAS No. ]:
2376824-92-7

[ Name ]:
TRPA1-IN-1

Biological Activity

[Description]:

TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Others

[References]

[1]. Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64(7):3843-3869.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇ClN₆O₃

[ Molecular Weight ]:
412.83

Related Compounds