5-hydroxytryptoline

Names

[ Name ]:
5-hydroxytryptoline

[Synonym ]:
6-Hydroxytetrahydronorharmane
Plectocomine
6-hydroxy-THBC
2,3,4,9-tetrahydro-1h-|A-carbolin-6-ol
5-Hydroxytryptoline

Chemical & Physical Properties

[ Density]:
1.314g/cm3

[ Boiling Point ]:
424.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₁₂N₂O

[ Molecular Weight ]:
188.22600

[ Flash Point ]:
210.5ºC

[ Exact Mass ]:
188.09500

[ PSA ]:
48.05000

[ LogP ]:
1.84800

[ Vapour Pressure ]:
8.33E-08mmHg at 25°C

[ Index of Refraction ]:
1.709

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV1050000

CHEMICAL NAME :: 1H-Pyrido(3,4-b)indol-6-ol, 2,3,4,9-tetrahydro-

CAS REGISTRY NUMBER :: 23778-34-9

BEILSTEIN REFERENCE NO. :: 0643872

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H12-N2-O

MOLECULAR WEIGHT :: 188.25

WISWESSER LINE NOTATION :: T B656 EM HMT&&J LQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 45,729,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 45,729,1978

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%