KB02-SLF
Names
[ CAS No. ]:
2384184-40-9
[ Name ]:
KB02-SLF
Biological Activity
[Description]:
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader (molecular glue). KB02-SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-SLF.
Chemical & Physical Properties
[ Molecular Formula ]:
C50H65ClN4O12
[ Molecular Weight ]:
949.52
Safety Information
[ Hazard Codes ]:
Xi