TLR7/8 agonist 4 hydroxy-PEG10-acid

Names

[ CAS No. ]:
2388520-17-8

[ Name ]:
TLR7/8 agonist 4 hydroxy-PEG10-acid

Biological Activity

[Description]:

TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Traditional Cytotoxic Agents


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C41H68N6O12

[ Molecular Weight ]:
837.01

Related Compounds