Thioflavine T
Names
[ CAS No. ]:
2390-54-7
[ Name ]:
Thioflavine T
[Synonym ]:
2-[4-(Dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride
THIOFLAVINET,TG
EINECS 219-228-9
THIOFLAVINE TG
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzo[d]thiazol-3-ium chloride
thioflavin T
MFCD00011944
Acronol Yellow T
SETOFLAVINE T
Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (1:1)
BASIC YELLOW 1
Setoflavin T
Thioflavine TCN
Thioflavine T
Benzothiazolium, 2-[4- (dimethylamino)phenyl]-3,6-dimethyl-, chloride
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[Kinase Assay]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Melting Point ]:
212ºC
[ Molecular Formula ]:
C17H19ClN2S
[ Molecular Weight ]:
318.864
[ Exact Mass ]:
318.095734
[ PSA ]:
35.36000
[ LogP ]:
0.77120
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
32041300
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Molecular Neurodegeneration 10 , 8, (2015)
Aggregation and aggregation-mediated formation of toxic alpha synuclein (aSyn) species have been linked to the pathogenesis of sporadic and monogenic Parkinson's disease (PD). A novel H50Q mutation of...
β-cyclodextrin and curcumin, a potent cocktail for disaggregating and/or inhibiting amyloids: a case study with α-synuclein.Biochemistry 53(25) , 4081-3, (2014)
Aggregation of α-synuclein has been implicated in Parkinson's disease (PD). While many compounds are known to inhibit α-synuclein aggregation, dissolution of aggregates into their constituent monomers...
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.Nat. Commun. 6 , 6176, (2015)
In Alzheimer's disease (AD), β-amyloid (Aβ) plaques are tightly enveloped by microglia processes, but the significance of this phenomenon is unknown. Here we show that microglia constitute a barrier w...