SN38 NHS ester

Names

[ Name ]:
SN38 NHS ester

Biological Activity

[Description]:

SN38 NHS ester is the NHS ester derivative of SN38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis. SN38 NHS ester can be used for the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Asa Wallin, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₂₇N₃O₁₀

[ Molecular Weight ]:
589.55

SN38 NHS ester

Names

Biological Activity

Chemical & Physical Properties

Related Compounds