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ddATP

Names

[ CAS No. ]:
24027-80-3

[ Name ]:
ddATP

[Synonym ]:
2',3'-Dideoxy-ATP
2',3'-dideoxyadenosine-5'-triphosphate
ddATP
2',3'-Dideoxyadenosine triphosphate
Adenosine 5'-(tetrahydrogen triphosphate),2',3'-dideoxy
2',3'-ddATP

Biological Activity

[Description]:

ddATP is a dideoxynucleotide, acts as a chain-elongating inhibitor of DNA polymerase, used for Sanger method for DNA sequencing[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Research Areas >> Others

[References]

[1]. van der Vliet PC, et al. Role of DNA polymerase gamma in adenovirus DNA replication. Mechanism of inhibition by 2',3'-dideoxynucleoside 5'-triphosphates. Biochemistry. 1981 Apr 28;20(9):2628-32.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H16N5O11P3

[ Molecular Weight ]:
475.18200

[ Exact Mass ]:
475.00600

[ PSA ]:
268.10000

[ LogP ]:
1.01060

Related Compounds