Antimycobacterial agent-1

Names

[ CAS No. ]:
2409926-02-7

[ Name ]:
Antimycobacterial agent-1

Biological Activity

[Description]:

Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC: 1 μg/ml (M. tuberculosis)[1]


[References]

[1]. Trotsko N, et al. Synthesis and antimycobacterial activity of thiazolidine-2,4-dione based derivatives with halogenbenzohydrazones and pyridinecarbohydrazones substituents. Eur J Med Chem. 2020;189:112045.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H12N4O5S

[ Molecular Weight ]:
396.38

Related Compounds