Calpain Inhibitor-2

Names

[ CAS No. ]:
2413962-65-7

[ Name ]:
Calpain Inhibitor-2

Biological Activity

[Description]:

Calpain inhibitors are lipophilic and show moderate to good antiproliferative activity in vitro compared with melanoma cell lines (a-375 and b-16f1) and PC-3 prostate cancer cells. In addition, a member of this group (compound 3) expressed 2 μ M concentration inhibited the invasion of DU-145 cells by 80%.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Donkor IO,et al. Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorg Med Chem. 2020 May 1;28(9):115433.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H33N3O5S

[ Molecular Weight ]:
499.62

Related Compounds