PI3Kα-IN-7
Names
[ CAS No. ]:
2417098-53-2
[ Name ]:
PI3Kα-IN-7
Biological Activity
[Description]:
PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis[1].
[Related Catalog]:
[Target]
PI3Kα
PI3Kβ
[In Vitro]
PI3Kα-IN-7 (Compound A12) shows potent antitumor activities against HCT116, PC-3, MCF-7, A549 and MDA-MB-231 cell lines with IC50 values of 3.24 μM, 14.37 μM, 7.39 μM, 7.10 μM, and 16.85 μM, respectively[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C17H22N8O2S
[ Molecular Weight ]:
402.47