hCAXII-IN-3

Names

[ CAS No. ]:
2417232-24-5

[ Name ]:
hCAXII-IN-3

Biological Activity

[Description]:

hCAXII-IN-3 (Compound 6o) is a selective human carbonic anhydrase XII (hCAXII) inhibitor with a Ki of 10.0 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[Target]

Ki: 10.0 nM (hCAXII), 757.8 nM (hCAIX), 829.8 nM (hCA I), 9688 nM (hCA II)[1]


[References]

[1]. Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H20BrN5O3S

[ Molecular Weight ]:
562.44

Related Compounds