EGFR-IN-51
Names
[ CAS No. ]:
2418549-32-1
[ Name ]:
EGFR-IN-51
Biological Activity
[Description]:
EGFR-IN-51 (Compound 6) is a potent EGFR inhibitor with IC50 values of 0.493, 102.60 and 461.63 µM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-51 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].
[Related Catalog]:
[Target]
EGFR:0.493 μM (IC50)
EGFRL858R:102.60 μM (IC50)
EGFRT790M:461.63 μM (IC50)
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H15N3O2S
[ Molecular Weight ]:
373.43