AChE-IN-20

Names

[ CAS No. ]:
2428389-65-3

[ Name ]:
AChE-IN-20

Biological Activity

[Description]:

AChE-IN-20 (compound M26) is a potent AChE inhibitor with IC50 value of 397.32 nM and with Ki value of 335.76 nM. AChE-IN-20 shows inhibition potency against hCA I , hCA II and α-GLY with IC50 values of 84.14, 69.24 and 52.08 nM and with Ki values of 97.86, 76.23 and 57.93 nM, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Lolak N, et al. Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem. 2020 Jul;100:103897.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H20N8O6S2

[ Molecular Weight ]:
556.57

Related Compounds