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PROTAC IRAK4 degrader-7

Names

[ CAS No. ]:
2432994-31-3

[ Name ]:
PROTAC IRAK4 degrader-7

Biological Activity

[Description]:

PROTAC IRAK4 degrader-7 (Compound I-417) is an orally active PROTAC IRAK4 degrader with antitumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> IRAK

Signaling Pathways >> PROTAC >> PROTAC

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK

[Target]

IRAK4

[References]

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. Patent WO2020113233A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₄H₄₉F₂N₁₁O₆

[ Molecular Weight ]:
865.93

Related Compounds