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Nagilactone C

Names

[ CAS No. ]:
24338-53-2

[ Name ]:
Nagilactone C

[Synonym ]:
3H,8H-Furo[2',3',4':4,5]oxireno[7,8]naphtho[2,1-c]pyran-3,8-dione, 1a,2,2a,4a,4b,5,9b,9c-octahydro-2,5-dihydroxy-2a,9b-dimethyl-6-(1-methylethyl)-, (1aR,2R,2aR,4aS,4bR,5R,9bS,9cS)-
(1aR,2R,2aR,4aS,4bR,5R,9bS,9cS)-2,5-Dihydroxy-6-isopropyl-2a,9b-dimethyl-1a,2,2a,4a,4b,5,9b,9c-octahydro-3H,8H-oxireno[5,6][2]benzofuro[7,1-fg]isochromene-3,8-dione

Biological Activity

[Description]:

Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. K Shrestha, et al. An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. Phytomedicine. 2001 Nov;8(6):489-91.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
667.3±55.0 °C at 760 mmHg

[ Melting Point ]:
290℃

[ Molecular Formula ]:
C19H22O7

[ Molecular Weight ]:
362.37

[ Flash Point ]:
244.9±25.0 °C

[ Exact Mass ]:
362.136566

[ PSA ]:
109.50000

[ LogP ]:
1.37

[ Vapour Pressure ]:
0.0±4.6 mmHg at 25°C

[ Index of Refraction ]:
1.630

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds