BnO-PEG6-OH

Names

[ Name ]:
BnO-PEG6-OH

[Synonym ]:
1-Phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol
2,5,8,11,14,17-Hexaoxanonadecan-19-ol, 1-phenyl-
Hexaethylene Glycol Monobenzyl Ether
1-hydroxy-3,6,9,12,15,18-hexaoxa-19-phenyl-nonadecane
2-[2-[2-[2-[2-[2-(Benzyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol

Biological Activity

[Description]:

BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Shaoyun Xiang, et al. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses there. Patent WO2016197946A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
473.6±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₃₂O₇

[ Molecular Weight ]:
372.453

[ Flash Point ]:
240.3±27.3 °C

[ Exact Mass ]:
372.214813

[ PSA ]:
75.61000

[ LogP ]:
-0.54

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.494

BnO-PEG6-OH

Names

Biological Activity

Chemical & Physical Properties

MSDS

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Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds