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GLYCOLITHOCHOLIC ACID SODIUM SALT

Names

[ CAS No. ]:
24404-83-9

[ Name ]:
GLYCOLITHOCHOLIC ACID SODIUM SALT

[Synonym ]:
glycolithocholic acid sodium salt
SODIUM GLYCOLITHOCHOLATE
GLYCOLITHOCHOLIC ACID SODIUM

Biological Activity

[Description]:

Glycolithocholic acid sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC)[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Tanno N, et, al. Biliary lipid composition in heterozygous familial hypercholesterolemia and influence of treatment with probucol. Dig Dis Sci. 1994 Jul;39(7):1586-91.

[2]. Ang ZH, et, al. Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis. World J Gastroenterol. 2021 Jun 28;27(24):3609-3629.

Chemical & Physical Properties

[ Boiling Point ]:
619.7ºC at 760 mmHg

[ Molecular Formula ]:
C26H42NNaO4

[ Molecular Weight ]:
455.60600

[ Flash Point ]:
328.6ºC

[ Exact Mass ]:
455.30100

[ PSA ]:
89.46000

[ LogP ]:
3.67950

Related Compounds