3',5'-di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside

Names

[ CAS No. ]:
244184-56-3

[ Name ]:
3',5'-di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside

Biological Activity

[Description]:

3',5'-Di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H18ClN5O6

[ Molecular Weight ]:
399.79

[ Exact Mass ]:
399.09500

[ PSA ]:
140.68000

[ LogP ]:
1.05030

Precursor & DownStream

Precursor

DownStream

Related Compounds