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celaphanol a

Names

[ CAS No. ]:
244204-40-8

[ Name ]:
celaphanol a

[Synonym ]:
6,12,13-Trihydroxypodocarpa-5,8(14),9(11),12-tetraen-7-one
9(1H)-Phenanthrenone, 2,3,4,4a-tetrahydro-6,7,10-trihydroxy-1,1,4a-trimethyl-, (4aR)-

Biological Activity

[Description]:

Celaphanol A is a diterpene that can be isolated from the root bark of Celastrus orbiculatus. Celaphanol A shows neuroprotective effect against a hydrogen peroxide-induced cytotoxicity in PC12 cells[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Wang LY, et al. (M)- and (P)-bicelaphanol A, dimeric trinorditerpenes with promising neuroprotective activity from Celastrus orbiculatus. J Nat Prod. 2013 Apr 26;76(4):745-9.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
532.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H20O4

[ Molecular Weight ]:
288.338

[ Flash Point ]:
290.1±26.6 °C

[ Exact Mass ]:
288.136169

[ PSA ]:
77.76000

[ LogP ]:
3.86

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.644

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds