NAEPA

Names

[ CAS No. ]:
24435-25-4

[ Name ]:
NAEPA

[Synonym ]:
2-[[(E)-octadec-9-enoyl]amino]ethyl dihydrogen phosphate

Biological Activity

[Description]:

NAEPA, a phosphate-mimetic derivative, is a lysophosphatidic acid (LPA) receptor agonist[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> LPL Receptor

[References]

[1]. Santos WL, et al. Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid. Bioorg Med Chem Lett. 2004;14(13):3473-3476.

Chemical & Physical Properties

[ Melting Point ]:
75.8-84.0ºC

[ Molecular Formula ]:
C₂₀H₄₀NO₅P

[ Molecular Weight ]:
405.50900

[ Exact Mass ]:
405.26400

[ PSA ]:
109.16000

[ LogP ]:
6.08970

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor.

Exp. Biol. Med. 234 , 986-93, (2009)

Lysophosphatidic acid (LPA) has been shown to be a potent modulator of prostaglandin (PG) secretion during the luteal phase of the estrous cycle in the bovine endometrium in vivo. The aims of the pres...