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(R)-L888607

Names

[ CAS No. ]:
2446042-90-4

[ Name ]:
(R)-L888607

Biological Activity

[Description]:

(R)-L 888607 is the inactive isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67(6):1834-9.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H15ClFNO2S

[ Molecular Weight ]:
375.84

[ Storage condition ]:
2-8°C, stored under nitrogen

Related Compounds